Senkyunolide IDISCONTINUED PLEASE SEE S213255
Senkyunolide I
CAS: 94596-28-8
Molecular Formula: C12H16O4
Senkyunolide IDISCONTINUED PLEASE SEE S213255 - Names and Identifiers
Senkyunolide IDISCONTINUED PLEASE SEE S213255 - Physico-chemical Properties
| Molecular Formula | C12H16O4 |
| Molar Mass | 224.25 |
| Density | 1.28 |
| Boling Point | 444.8±45.0 °C |
| Specific Rotation(α) | 0°（c=0.79，chloroform） |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | Colorless oil |
| Storage Condition | 2-8℃ |
| MDL | MFCD20527301 |
| Physical and Chemical Properties | Slightly yellow oil, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Ligusticum chuanxiong. |
Senkyunolide IDISCONTINUED PLEASE SEE S213255 - Reference
| Reference Show more | 1. Lou Yan, Jia Ying, He Bosai, et al. Simultaneous determination of five components in suanzaoren decoction by RP-HPLC dual-Wavelength Spectrophotometry [J]. Journal of Shenyang Pharmaceutical University 2013(07):47-52. 2. Guo Li, Wu Sha, Wang Jing, et al. Study on preparation technology and content determination of main components of xiongfu dropping pills [J]. Chinese Journal of Traditional Chinese Medicine, 2019, v.34(12):402-405. 3. Chen ran, Yin Dandan, Yang Mo, etc. Comparison of six components in fresh and Ligusticum Chuanxiong by ultra performance liquid chromatography [J]. Journal of Anhui College of Traditional Chinese Medicine, 2019, 038(006):84-88. 4. Shi Haipei, Bao Beihua, Huang Shengliang, Wang Guoqiang, left Wu Peng, Yan Hui, Zhang Li. Study on fingerprint and pattern recognition of Angelica sinensis decoction pieces [J]. Shi Zhen, National Medicine, 2019,30(02):364-368. 5. Zhao Rong, Jiang Jun, Xiao Shichang, et al. Taohong Siwu decoction reverses glucocorticoid-induced osteoporosis in zebrafish model [J]. Chinese Journal of Pharmacy, 2019, 54(02):143-150. 6. Wang Zhenheng, Wang Yinquan, Fan Qin, et al. Effects of ultraviolet-B radiation on phthalide content in angelica sinensis [J]. Journal of Gansu University of Chinese Medicine, 2019(6). 7. Deng Xueqi, Guan Xiaojun, Huang Na, Li Jun. Simultaneous determination of eight components in angelica sinensis by HPLC [J]. Chinese patent medicine 2020 42(08):2075-2079. 8. Mao Wendian, Li Lingling, Qi Wense, Su Zhizhi, Deng Changqing, Zhou Long. Effect of different compatibility of radix astragali and radix angelicae sinensis on the dissolution of six main effective components [J]. Journal of Hunan University of Traditional Chinese Medicine, 2021,41(03):350-354. 9. Deng Xueqi, Guan Xiaojun, Huang Na Na, Li Jun. Simultaneous determination of eight components in angelica sinensis by HPLC [J]. Chinese traditional medicines, 2020,42(08):2075-2079. 10. Hu Yang, Ding Xiaoqian, Yan Hui, Wu Yinzhi, Peng Guoping, Huang Shengliang. Study on quality standard of Ligusticum Chuanxiong [J]. Chinese traditional medicines, 2021,43(03):692-699. 11. Peng Tong, Wang Yinquan, Zhang Yali, Yan Shunan, Qin Jun, Ma Qin state. Comparison of 8 effective components between Angelica sinensis of Linqu and Minxian County [J]. Journal of Gansu University of Chinese Medicine, 2020,37(06):29-33. 12. Zulfajri, Muhammad. "Influences of allosteric effects on the structure and function of human hemoglobin." (2014). 13. Li J, Liu H, Yang Z, Yu Q, Zhao L, Wang Y. Synergistic Effects of Cryptotanshinone and Senkyunolide I in Guanxinning Tablet Against Endogenous Thrombus Formation in Zebrafish. Front Pharmacol. 2021;11:622787. Published 2021 Jan 14. doi:10.3389/fphar.2020.6 14. Han, C. H. E. N., et al. "Chemical profile of the active fraction of Yi-Gan San by HPLC-DAD-Q-TOF-MS and its neuroprotective effect against glutamate-induced cytotoxicity ." Chinese journal of natural medicines 12.11 (2014): 869-880.https://doi.org/10.1016/ 15. [IF=4.379] Chen Wei-Ren et al."Phthalide Derivatives from Angelica Sinensis Decrease Hemoglobin Oxygen Affinity: A New Allosteric-Modulating Mechanism and Potential Use as 2,3-BPG Functional Substitutes."Sci Rep-Uk. 2017 Jul;7(1):1-15 16. [IF=3.922] Nating Zhang et al."Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing a Chinese Herbal Injection Used in Sepsis Management."Drug Metab Dispos. 2018 Jun;46(6):823-834 17. [IF=3] Han CHEN et al."Chemical profile of the active fraction of Yi-Gan San by HPLC-DAD-Q-TOF-MS and its neuroprotective effect against glutamate-induced cytotoxicity."Chin J Nat Medicines. 2014 Nov;12:869 18. [IF=5.81] Jun Li et al."Synergistic Effects of Cryptotanshinone and Senkyunolide I in Guanxinning Tablet Against Endogenous Thrombus Formation in Zebrafish."Front Pharmacol. 2020; 11: 622787 19. [IF=5.34] Tao-Fang Cheng et al."Compound Dan Zhi tablet attenuates experimental ischemic stroke via inhibiting platelet activation and thrombus formation."Phytomedicine. 2020 Dec;79:153330 20. [IF=4.36] Jing Chen et al."Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling."J Ethnopharmacol. 2021 Sep;:114667 |
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